After making a diagnosis and prescribing a treatment, rheumatologists might continue ordering anti-CCP tests to help track your disease activity. Learn more here. The joint is usually stiff in the morning, but will begin to loosen up during the rest of the day. This means that the patients immune system produces antibodies that identify the patients cells as foreign material and as a result, attack its own normal cells. If you have suggestive signs of rheumatoid arthritis and positive results in the anti-CCP test but negative results in the RA test, or if you are symptomatic with weak results in both tests, it is likely that you are in the early phase of the disease or that it will develop in the future. anti-CCP is very specific of RA, but you can found them in other rjeumatic diseases: - Palindromic rheumatism: 56% (Salvador G. Rheumatology 2003;42:972) - Psoriatic arthritis; 12% (worse. High titers of anti-CCPcorresponded with the ACR scores. Learn more here. It may mean a person does not have enough anti-CCP in their blood to create a positive result, even though they do have RA. These include: You may also need this test if other tests couldn't confirm or rule out a diagnosis of rheumatoid arthritis. A negative result by itself does not rule out the disease. Frustrated by the lack of good information and tools, Joe decided to embark on a learning journey to decode his DNA and track his biomarkers in search of better health. Does high anti CCP level mean a more aggressive RA? : r/rheumatoid - Reddit As a result, this test also helps doctors pursue specific and possibly more aggressive treatment options. Hey there. If the anti-CCP is positive, a doctor may order a rheumatoid factor test, too. If you test positive for anti-CCP antibodies but not rheumatoid factor (RF) and are experiencing any symptoms of the disease, you may have RA. Link Between Autoantibody Levels and Disease Activity in Rheumatoid This usually takes less than five minutes.